Anxiety symptoms
Evidence basis: randomised trials
Meta-analytic and systematic-review evidence consistently points to reduced anxiety after progressive muscle relaxation training, but the effect estimates are large, imprecise and highly heterogeneous.
Population: Adults across mixed settings: 31 randomized trials with 2,277 patients in the 2026 meta-analysis; 27 studies in the 2008 relaxation meta-analysis (1997-2007); 46 publications from 16 countries covering more than 3,402 adults in the 2024 systematic review, mostly university students, nurses and healthcare workers, older adults and patients with physical illness.
Research details
Summary
Meta-analytic and systematic-review evidence consistently points to reduced anxiety after progressive muscle relaxation training, but the effect estimates are large, imprecise and highly heterogeneous. A 2026 meta-analysis of 31 randomized trials (2,277 patients) reported an anxiety standardized mean difference of -1.11 (95% CI -1.69 to -0.53, I2 = 85%), and a 2008 meta-analysis of 27 relaxation studies found a between-group Cohen's d of .51 (95% CI .46 to .634). A 2024 systematic review of 46 publications covering more than 3,402 adults concluded that PMR reduces stress, anxiety and depression. Most individual trials compare PMR with routine care or no intervention rather than an active control.
Why this certainty
Rated Limited: the direction is consistent across two independent meta-analyses and one large systematic review, but heterogeneity is very high (I2 = 85%, I2 = 92.1% for sleep in the same review), effect sizes are implausibly large for a relaxation intervention, and the comparator is usually no treatment or routine care rather than an active control, so non-specific effects of attention and expectation are not excluded. Small samples and high risk of bias limit confidence in the magnitude.
Limitations
Much of the literature is older with small samples and unclear blinding; in the 2024 review, designs were a mix of randomized and quasi-experimental studies, many anxiety findings rest on within-group pre-post change rather than between-group comparison, and several included trials (for example Avants 1990, Jermaina 2022, Mustafa 2021) found no significant anxiety reduction. Reporting of allocation concealment and blinding at item level could not be confirmed from the material retrieved.
Effect estimate
Anxiety: SMD -1.11 (95% CI -1.69 to -0.53; I2 = 85%) in 31 RCTs (Donato 2026). Relaxation training (including Jacobson's progressive relaxation, autogenic training, applied relaxation and meditation) for anxiety: between-group Cohen's d .51 (95% CI .46 to .634) and within-group d .57 (95% CI .52 to .68) in 27 studies (Manzoni 2008).
- Progressive muscle relaxation technique improves sleep quality and mental health: A systematic review and meta-analysis of randomized controlled trials
- Relaxation training for anxiety: a ten-years systematic review with meta-analysis
- Efficacy of Progressive Muscle Relaxation in Adults for Stress, Anxiety, and Depression: A Systematic Review
- Psychological interventions for depression and anxiety in patients with coronary heart disease, heart failure or atrial fibrillation
