Total and LDL cholesterol
Evidence basis: randomised trials
Paper filtering produces lower LDL than unfiltered boiled coffee in high-intake trials.
Population: Healthy adults: 64 volunteers drinking six cups daily, 20 volunteers in four-week crossover periods, and 107 young adults in a 12-week trial.
Research details
Summary
A randomized trial in 64 healthy volunteers compared unfiltered boiled coffee with the same coffee passed through paper filters. Unfiltered coffee raised LDL by 0.41 mmol/L (95% CI 0.16 to 0.66) relative to filtered coffee. A 20-person randomized crossover also found higher total and LDL cholesterol with boiled coffee, and filtering removed more than 80% of its lipid-soluble material. In a separate 107-person trial the LDL difference was 0.39 mmol/L, but its confidence interval crossed the null (-0.04 to 0.82); filtered coffee did not significantly differ from no coffee.
Why this certainty
Moderate certainty reflects several direct randomized comparisons and a tested filtering mechanism. Certainty is limited by small samples, short follow-up and uncertainty about typical lower-volume consumption.
Limitations
These older trials mainly tested strong boiled coffee at high daily volumes, so the magnitude should not be assumed for one cup or every brewing method. The 107-person trial had an imprecise LDL estimate. Cholesterol is a risk factor; these trials did not measure heart attacks or mortality.
Effect estimate
Unfiltered minus paper-filtered LDL: +0.41 mmol/L (95% CI 0.16 to 0.66).
