Sex and menopausal status influence human dietary requirements for the nutrient choline.
Fischer LM, daCosta KA, Kwock L, Stewart PW, Lu TS, Stabler SP, Allen RH, Zeisel SH. · The American journal of clinical nutrition · 2007
Include suitable choline-containing foods as part of a varied eating pattern.
Choline supports normal nutrient adequacy. NIH guidance identifies food sources, and a controlled depletion-and-repletion study demonstrates that severe deficiency can cause reversible organ dysfunction. That experiment is not a trial of adding an egg each day to an already adequate diet, and it does not establish a cognition benefit. This Basic entry gives food guidance with traceable background sources and no graded outcome assessment.
Scientific evidence
Outcome assessments based on research, including its uncertainties and limitations.
This entry is an overview. Its background references do not establish whether the practice works.
What people say
Public statements, with positions specific to each source and topic. These views do not determine the scientific evidence assessment.
What the research shows ↑
Public figure
Discusses the essential nutrient choline. The food-adequacy entry is separate from Alpha-GPC supplementation or claims of cognitive enhancement.
Direct source · Podcast · YouTube · Chapter verified
Chapter heading checked; the full statement and its context have not been verified.
The Diary Of A CEO — Anti-Aging Expert: Missing This Vitamin Is Like Smoking! The Truth About Creatine! - Rhonda Patrick (opens in a new tab)Published Play at 2:43:02
Patrick describes eating eggs as a source of choline during her pregnancy. The original video is a members-only Q&A; her public publisher transcript contains the statement.
Direct source · Podcast · YouTube · Transcript verified
FoundMyFitness — Member's Only FoundMyFitness Q&A #35 (4/30/22) with Dr. Rhonda Patrick (opens in a new tab)Published Play at 1:02:32
These support context and precautions; they are separate from assessed outcome sources.
Fischer LM, daCosta KA, Kwock L, Stewart PW, Lu TS, Stabler SP, Allen RH, Zeisel SH. · The American journal of clinical nutrition · 2007
NIH Office of Dietary Supplements · NIH Office of Dietary Supplements · 2022
Community
Have you tried this? What helped or made it difficult?
Reader experiences are separate from the scientific evidence. Explore all discussions
No discussions yet.
Be the first to ask a question or share your experience.
Sign in to vote or join the discussion.
Explore other habits in a shared category. Each has its own evidence and precautions.
Revision 2 · Approved for publication · Codex (publication approval explicitly authorized by site owner; category migration)
Prepared and checked with AI. Publication approval does not imply independent expert review. Request a correction.
New revision-1 Basic draft. Evidence and original-video attribution are separate. Check practice matching, population and formulation limits, null results and safety wording before independent approval. Sources: fischer-2007-choline-depletion, nih-2022-choline-food-guidance. Publication release 2026-10-04: site owner authorized a bounded AI audit and release of this exact revision. See docs/release-audit-2026-10-04.md for source-check findings and limits. No independent health-professional or peer review is claimed. Category migration 2026-10-04: removed the separate goals field; categories: Nutrition → Nutrition. Research assessments, sources, guidance, precautions, and evidence review dates are unchanged. This revision awaits publication approval; no new evidence review is claimed. Publication approval 2026-10-04: site owner explicitly accepted all current category-migration revisions for deployment and requested that remaining limitations be retained in docs/content-review-backlog.md. Approval applies to this exact content revision. No new evidence review, independent expert review, or clinical validation is claimed; existing precautions and disclosures remain in effect.